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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFC2
All Species:
36.06
Human Site:
S241
Identified Species:
56.67
UniProt:
P35250
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35250
NP_002905.2
354
39157
S241
N
N
L
Q
S
T
F
S
G
F
G
F
I
N
S
Chimpanzee
Pan troglodytes
XP_001149874
354
39149
S241
N
N
L
Q
S
T
F
S
G
F
G
F
I
N
S
Rhesus Macaque
Macaca mulatta
XP_001082511
352
38844
S239
N
N
L
Q
S
T
F
S
G
F
G
F
I
N
S
Dog
Lupus familis
XP_546916
352
38707
S239
N
N
V
Q
S
T
F
S
G
F
G
F
I
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUK4
349
38706
S236
N
N
L
Q
S
T
F
S
G
F
G
Y
I
N
S
Rat
Rattus norvegicus
Q641W4
349
38638
S236
N
N
L
Q
S
T
F
S
G
F
G
Y
I
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516769
407
45006
S294
N
N
L
Q
S
T
Y
S
G
F
G
F
I
N
S
Chicken
Gallus gallus
P53033
359
39688
S246
N
N
L
Q
S
T
Y
S
G
F
G
F
I
N
S
Frog
Xenopus laevis
NP_001084837
348
38438
A236
N
N
V
Q
S
T
C
A
G
F
G
F
V
N
S
Zebra Danio
Brachydanio rerio
NP_001013344
349
39005
S236
N
N
L
Q
S
T
N
S
G
F
G
Y
I
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P53034
331
37155
Q221
N
N
L
Q
S
T
A
Q
G
F
G
D
I
T
A
Honey Bee
Apis mellifera
XP_623937
350
39000
N241
N
N
L
Q
S
T
H
N
G
F
N
H
V
N
S
Nematode Worm
Caenorhab. elegans
P34429
368
41157
M243
N
T
L
Q
S
T
A
M
S
F
D
T
V
S
E
Sea Urchin
Strong. purpuratus
XP_790650
352
38724
A238
N
N
L
Q
S
T
Y
A
G
F
G
S
I
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40339
323
36131
A214
N
N
L
Q
S
T
V
A
G
H
G
L
V
N
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98
93.5
N.A.
92.3
91.5
N.A.
76.6
87.7
86.4
82.7
N.A.
68.9
67.2
35
71.1
Protein Similarity:
100
99.7
98.8
96.6
N.A.
95.4
94.9
N.A.
81.5
91.6
91.5
88.4
N.A.
79.6
78.8
51.6
85.5
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
73.3
86.6
N.A.
66.6
66.6
40
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
93.3
N.A.
73.3
80
53.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
54.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
72.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
14
20
0
0
0
0
0
0
14
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
40
0
0
94
0
47
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
94
0
87
0
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
7
0
7
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
74
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
87
0
0
0
0
0
0
0
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
100
94
0
0
0
0
7
7
0
0
7
0
0
80
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
100
0
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
100
0
0
60
7
0
0
7
0
7
80
% S
% Thr:
0
7
0
0
0
100
0
0
0
0
0
7
0
14
0
% T
% Val:
0
0
14
0
0
0
7
0
0
0
0
0
27
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
20
0
0
0
0
20
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _